Immunomodulator effect of ketamine on rat models of sepsis (fecal induced peritonitis): Eosinophil and monocyte modulation

  • Aswoco Andyk Asmoro Jl. Jaksa Agung Suprapto no.2, Malang, East Java, Indonesia.
  • Wiwi Jaya Jl. Jaksa Agung Suprapto no.2, Malang, East Java, Indonesia
  • Asna Nasiqah Jl. Jaksa Agung Suprapto no.2, Malang, East Java, Indonesia
  • Muhammad Rodli Jl. Jaksa Agung Suprapto no.2, Malang, East Java, Indonesia
DOI: https://doi.org/10.35975/apic.v24i3.1279
Keywords: Eosinophil, Fecal induced peritonitis, Immunomodulation, Ketamine, Monocyte, Sepsis

Abstract

Sepsis is a result of dysregulated inflammation and it affects the inflammatory mediator cell production. Ketamine has an immunomodulatory effect and it can be used in the sepsis immunotherapy. We conducted this study to determine the effect of ketamine on the number of eosinophils and monocytes in the rat model of sepsis.

Published
08-07-2020
How to Cite
Asmoro, A., Jaya, W., Nasiqah, A., & Rodli, M. (2020). Immunomodulator effect of ketamine on rat models of sepsis (fecal induced peritonitis): Eosinophil and monocyte modulation. Anaesthesia, Pain & Intensive Care, 24(3), 279-283. https://doi.org/10.35975/apic.v24i3.1279
Issue
Vol 24 No 3 (2020): July-Sep
Section
ORIGINAL RESEARCH