Evaluation of the effects of dexmedetomidine on liver damage secondary to renal ischemia-reperfusion

  • Kartal Seyfi Assisstent Professor, Department of Anesthesiology and Reanimation, Trabzon Kanuni Education and Research Hospital, University of Healthy Sciences, Trabzon, (Turkey)
  • Şen Ahmet Associate Professor, Department of Anesthesiology and Reanimation, Trabzon Kanuni Education and Research Hospital, University of Healthy Sciences, Trabzon, (Turkey)
  • Tümkaya Levent Associate Professor, Department of Medical Sciences, Histology, Embryology, Faculty of Medicine, University of Recep Tayyip Erdoğan, Rize, (Turkey)
  • Özdemir Abdullah Assisstent Professor, Department of Anesthesiology and Reanimation, Faculty of Medicine, University of Recep Tayyip Erdoğan, Rize, (Turkey)
  • Mercantepe Tolga Assisstent Professor, Department of Medical Sciences, Histology, Embryology, Faculty of Medicine, University of Recep Tayyip Erdoğan, Rize, (Turkey)
  • Yılmaz Adnan Professor, Department of Basic Sciences Biochemistry, Faculty of Medicine, University of Recep Tayyip Erdoğan, Rize, (Turkey)
DOI: https://doi.org/10.35975/apic.v24i2.1257
Keywords: Renal Ischemia, Reperfusion, Dexmedetomidine, Liver

Abstract

Background: The aim of this study was to evaluate the hepatic protective effects of dexmedetomidine in a rat model of renal ischemia-reperfusion injury

 Methodology: Rats were randomly divided into 3 equal groups (n = 6); control (C) group, ischemia / reperfusion (I/R) group, (D + I/R) group which dexmedetomidine was given and I/R was administered.

Published
06-24-2020
How to Cite
Seyfi, K., Ahmet, Şen, Levent, T., Abdullah, Özdemir, Tolga, M., & Adnan, Y. (2020). Evaluation of the effects of dexmedetomidine on liver damage secondary to renal ischemia-reperfusion. Anaesthesia, Pain & Intensive Care, 24(2), 205-214. https://doi.org/10.35975/apic.v24i2.1257
Issue
Vol 24 No 2 (2020): April 2020
Section
ORIGINAL RESEARCH