Case Reports

Electro-acupuncture for chronic pelvic pain: two interesting cases

Anastasios Petrou, MD, PhD1, Petros Tzimas, MD, PhD1, Georgios Papadopoulos, Dr, Med Habil2

 1Assistant professor; 2Professor

Department of Anesthesiology and Postoperative Intensive Care, Faculty of Medicine, School of Health Sciences, University of Ioannina, P.O. Box 1186, 45110, Ioannina, Hellas

Correspondence: Anastasios Petrou, MD, PhD, Department of Anesthesiology and Postoperative Intensive Care, Faculty of Medicine, School of Health Sciences, University of Ioannina, P.O. Box 1186, 45110, Ioannina, Hellas; Tel: +306972728149; Fax: +302651007887; E-mail:


Neuropathic pain is a common cause of chronic pelvic pain. Its resistance to treatment, often challenges patient’s cooperation to prolonged and sometimes interventional schemes and necessitates constant search for alternative or complementary interventions.

In this case series, one elderly male patient who presented with persistent chronic pelvic pain after multiple abdominal operations did not respond to conventional medical treatment and acupuncture and requested discontinuation of treatment. Electro-acupuncture was applied as a last resort therapy and proved very effective in reducing pelvic pain; it permitted significant reduction in anti-depressant medication doses. A second case study refers to a young female patient who developed chronic pelvic pain after giving birth to a child. Various treatments proved unsuccessful in alleviation her pain.  She eventually responded to electro-acupuncture at multiple trigger points in the abdominal wall.

Key words: Chronic pelvic pain; Electro-acupuncture; Adult
Citation: Petrou A, Tzimas P, Papadopoulos G. Electro-acupuncture for chronic pelvic pain: two interesting cases. Anaesth Pain & Intensive Care 2017;21(3):370-373
Revised version received –  27 August 2017; Reviewed & Accepted – 5 September 2017
Editor-in-Chief’s note: This case report was earlier published in December 2016 in Vol 20(4) of Anaesthesia, Pain & Intensive Care. This is improved version of the case report with revamped figures for better clarity. 


Chronic pelvic pain (CPP) is a benign pain syndrome of continuous or relapsing pain that derives from the pelvic cavity and persists for more than six months. Its association with intercourse or menstruation is possible but not causative. It affects approximately one in  seven women and in some studies comprises almost 10% of all referrals to gynecologists.1,2

Various diseases generate CPP, which has multiple clinical manifestations but an obscure etiology.3,4

The clinical approach is based on detailed patient history, meticulous physical examination and appropriate laboratory evaluation. Treatment interventions are phased, starting with less invasive methods and escalating to more aggressive techniques, according to well established algorithms.5

We present two cases of complicated CPP which recently presented to our pain clinic and were successfully treated.


An 80 years old male patient presented with severe pelvic pain. His surgical patient history included a trans-urethral prostate resection 6 months prior to his visit with subsequent diagnosis of prostate cancer (clinical stage T1a-N0-M0 at presentation). He was on gonadotropin-releasing hormone agonists and non-steroid anti-androgens. A few years ago, he had a partial hepatectomy for liver cancer, endoscopic large bowel polyps resection and an inguinal hernia repair. His medical history was significant for arterial hypertension, coronary artery disease and an abdominal aortic aneurysm managed medically.

His analgesia included paracetamol 1 g thrice daily orally and tramadol drops 400 mg once daily orally.

The patient had severe pelvic and back pain rated at 10 out of 10 on Numeric Rating Scale (NRS, calibrated as 0 = no pain, 10 worst imaginable pain) and episodes of caustic pain originating from the outer urethra meatus and referring to the lower hypogastrium and the lumbar region (Figure 1).

Quality of life was graded as 3 out of 8 using the Instrumental Activities of Daily Life scale (IADL). The patient was clearly on a moderate depression state (grade 20 on Beck Depression Inventory scale [BDI-II], 0-13: minimal, 14-19: mild, 20-28: moderate, 29-63: severe).

Acupuncture was begun using acupoints BL 31+, BL 32+, BL 33+, BL 34+, SP 6, KI 3, CV 6, GB 28+, ST 29+, CV 4 (for pelvic inflammation and pain) plus BL 23+, CV 2, CV 4, BL 40, KI 5, KI 7 (for the urinary bladder pain) with 0.25 X 25 mm needles without tonification or dispersion (Figures 2 & 3).

Figure 2: Electro-acupuncture points used in our cases


The intervention lasted 30 minutes but failed to alleviate pain and the patient denied further sessions. A per os regimen of venlafaxine venlafaxine (a selective serotonin and norepinephrine reuptake inhibitor) 37.5 mg twice daily, titrated to 75 mg twice daily, pregabalin 75 mg once daily titrated to 300 mg twice daily and tramadol/acetaminophen 2 x (37.5 mg + 325 mg) four times daily reduced pain by approximately 50% but offered no relief of the urethra pain. The patient was bedridden, disheveled, dizzy, and somnolent and requested discontinuation of medical treatment. After extensive discussion with the pain team, he consented for a series of electro-acupuncture sessions as a last resort option accompanied by tapering of medications to the lowest indicated doses.
Electro-acupuncture was administered sequentially at the same acupoints as in the initial trial (6 mA, 2Hz, 220 ms, Pointer Excel II, TENS PLUS IND.CO. Hong Kong). The point stimulation was applied for 30-60 seconds and the session lasted more than 90 minutes. The patient exhibited immediate and complete regression of pain at the pelvis and the lumbar region and significant relief of the urethra meatus pain by the first session. After 8 weekly electro-acupuncture sessions he was free of pain in the pelvis and the lumbar region but still had recurring micturition pain (NRS 3). He discontinued tramadol, acetaminophen and pregabalin, reduced his venlafaxine dose, started socializing out of home; his depression faded and his appearance was decent again.
At follow up at 72 months later he was happy and only complained about micturition pain (VAS 3).


A young (38 years old) woman 18 months after giving birth to her second child, developed a temporally increasing pain in the pelvis, lumbar back and left thigh (Figure 1).

Figure 1: Localization of pain (shaded areas) for Case 1 and 2


Subsequently diagnosed with endometriosis, she was treated with endoscopic ablation combined with excision of an ovary cyst, but the pain worsened after the operation. Then, the patient received medical treatment for suspected irritable bowel syndrome, but it failed to relieve her pain symptoms.

At presentation she had a painful facial expression and a left, forward bending of the torso, like protecting the left pelvic area. She complained of devastating pain (NRS 10) at the left hypogastrium, referring to the inner surface of the left thigh, the left labium majus and the left lower lumbar region and lower bowel distension. The pain was constant during the day and was aggravating during the night, preventing sleep in either supine or prone positions. She also reported a burning pain in her inner, left thigh.

At physical examination, the hypogastrium was very sensitive and painful. Palpation of the left rectus abdominis muscle below the umbilicus as well the left lateral margin of the hypogastrium (external oblique muscle) with a balsam oil lubricated thumb revealed multiple pin point nodes that triggered very intense pain and averted reporting of its radiation.

The application of 30-60 second sequential electro-acupuncture (6 mA, 2 Hz, 220 ms, AS Super4, Pointer Excel II, TENS PLUS IND.CO. Hong Kong) at more than 30 identified trigger points resulted in complete reversal of spontaneous and palpation induced pain. The sense of abdominal distention disappeared and the patient could sleep peacefully in any desired posture. The electro-acupuncture scheme was repeated at 12 and 24 hours and the patient was started on venflaxacine that was escalated up to 75 mg twice daily during the following weeks. Three months later, venflaxacine was reduced gradually and was discontinued six months after the electro-acupuncture session.

Two years later, the patient has no pain and does not receive medical treatment.


We reported two diverse cases of CPP – one had classic neuropathic pain (NP) and was resistant to medical treatment and one had myofascial syndrome of the abdominal wall muscles; both were treated with electro-acupuncture. The intervention was judged successful with long standing effects.

Chronic pelvic pain is a quite common, multifactorial clinical entity. Aside from gynecologic origin in women, it is important for the clinician to seek for other possible causes including NP and neuromuscular pelvic system disorders.

Acupuncture was proposed by World Health Organization (WHO) in 1982 as a potential treatment for NP.6 In our case, we chose a standardized protocol that is considered appropriate for CPP and potentially is equally effective to personalized approaches.7,8

Acupuncture and electro-acupuncture convey their analgesic effect through release of endorphins, encephalins, dynorphins, prostaglandins, serotonin and ACTH at the central nervous system. Activation of the autonomous sympathetic system and the gate mechanism at the substantia gelatinosa is thought to cancel propagation of painful stimuli to the sensory cortex.9,10 The success of electro-acupuncture trial (case 1), despite the failure of acupuncture six months earlier, could be attributed to the re-balancing of chi and the facilitating effect of the anti-epileptic and anti-depressant medications. Quality of life improvement can also be credited to both anti-depressant medications and the resolution of persistent pain.

The outcome of case 2 reveals the significance of painful points on the rectus abdominis and external oblique muscles as important triggers of CPP.11-13

Myofascial syndrome is actually a subset of neuropathic pain and refers to a regional, neuromuscular disorder with particular neurophysiologic origins and distinct diagnostic criteria.14,15 It predominantly affects women of any age.1 Muscle trigger points evolve in superficial and deep pelvic muscle groups during high energy demand (e.g., strenuous and protracted training, bad sitting or standing posture) that results in defective blood supply in certain muscle foci, disruption of sarcoplasmic reticulum and spillover of algogenic substances. Referred pain from trigger points can sometimes be misleading as it can arise even in the contralateral side of the abdomen or in quite distant areas of the body.15

Therapeutic interventions focus on the deactivation of trigger points. Medical treatment consists of weak analgesics, muscle relaxants, anti-inflammatory preparations in combination with physiotherapy, local anesthetic infiltrations, dry needling or ultrasonic treatment 16 and non-interventional options like TENS, laser and repetitive magnetic stimulation (rMS).16,17 Chronic cases can benefit from anti-depressants and botulism toxin.13


In our cases, electro-acupuncture proved effective in successfully suppressing both CPP cases. Clinicians should persistently urge to deliver effective treatments based on scientific evidence and judicious consideration. Further research is needed to confirm if electro-acupuncture can be a reasonable option for neuropathic CPP treatment.

Conflict of interest: No author has any competing interest with the material presented in the manuscript.
Author contributions:

AP & PT: literature search, drafting, review and final preparation of manuscript.

GP: literature search, drafting and final review of manuscript.


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